View abstract. You should not take AHCC if you are taking drugs that are substrates of cytochrome P450 2D6 or medications that are changed by the liver, as the supplement can decrease the drug's effect.6 Check with your pha… Int J Occup Med Environ Health. 2014 Jul;52(6):625-8. View abstract. If you still decide to use a shiitake mushroom supplement, or add large quantities of shiitake mushrooms to your diet, consult your physician first. Med Mycol. However, if you have a condition we talked about in this article, you should be aware. View abstract. Nippon Geka Gakkai Zasshi 1991;92(1):5-11. The LIVESTRONG Foundation and LIVESTRONG.COM do not endorse This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. 200-500/mm3. Horiguchi, M., Saito, A., and Sonoda, H. [A gastric cancer showing marked improvement (stage IV) with lentinan immunotherapy and 5-FU, MMC-chemotherapy]. A number of studies have shown that turkey tail mushrooms have immune boosting properties. Dermatol Online J. Hitosugi M, Kitamura O, Takatsu A, Yoshino Y. Autopsy case of duodenal obstruction from impacted mushroom. A standardized mixture of polysaccharides from shiitake mushroom (AHCC) activated immune cells in humans and animals with viral infections such as :Influenza B (in humans) Hepatitis C (in humans) Human Papillomavirus (in humans and mice)  Mushroom contains enough gas that can make the stomach discomfort. Surg.Oncol. Hiernickel C, Metz S, Elsner P. Shiitake dermatitis: an impressive case report. [A case of long survival with UFT and lentinan treatment in a patient with peritoneal metastasis of gastric carcinoma]. Shiitake Mushrooms Side Effects. 1992;14(1):43-47. 2015 Apr;40(3):332-3. It can cause stomach discomfort, blood abnormalities, and skin swelling (inflammation). Solaray Shiitake Mushroom 600 mg | 100 Count ... 2.0 out of 5 stars got side effects from this. Gan To Kagaku Ryoho 1988;15(4 Pt 2-1):827-833. The appropriate dose of shiitake mushroom depends on several factors such as the user's age, health, and several other conditions. Hibino, Y., Konishi, Y., Koike, J., Tabata, T., Ohashi, Y., and Sugano, N. Productions of interferon-gamma and nitrite are induced in mouse splenic cells by a heteroglycan-protein fraction from culture medium of Lentinus edodes mycelia. Side Effects of Shiitake Mushroom. 2012;2012:217164. View abstract. Gan To Kagaku Ryoho 1987;14(9):2787-2791. Br.J Dermatol. View abstract. View abstract. Wada T, Nishide T, Hatayama K, et al. Destroy Cancer Cells. Biosci.Biotechnol.Biochem. View abstract. Some of the shiitake mushroom side effects are as follows. View abstract. 1998;18(11):665-667. Verified Purchase. A study reported that handling or consuming raw shiitake mushrooms can lead to a skin rash called shiitake mushroom dermatitis, which is likely caused by polysaccharide lentinan  . Clin Toxicol (Phila). Dermatol Online J. Endoscopy. Yoshino, S., Oka, M., Hazama, S., and Suzuki, T. [Effect of intrapleural and/or intraperitoneal lentinan therapy on carcinomatous pleuritis and peritonitis with special reference to immunological evaluation]. View abstract. Kim HS, Kacew S, Lee BM. Hanaue, H., Tokuda, Y., Machimura, T., Kamijoh, A., Kondo, Y., Ogoshi, K., Makuuchi, H., Nakasaki, H., Tajima, T., Mitomi, T., and . View abstract. There are some side effects that are associated with shiitake mushrooms, including gastrointestinal distress, a worsening of autoimmune disease, sensitivity to the sun and allergic reactions. View abstract. Mushrooms may boost your memory. Information from this source is evidence-based and objective, and without commercial influence. Immunopharmacology 1998;40(3):187-198. Dermatol Reports. Gan To Kagaku Ryoho 1990;17(8 Pt 1):1517-1519. View abstract. The allergies caused by shiitake mushroom can affect your lungs, throat, nose, skin. Mushrooms are well known for their health benefits but on the other hand, it has some side effects also when consumed in excess or not fresh. Sia, G. M. and Candlish, J. K. Effects of shiitake (Lentinus edodes) extract on human neutrophils and the U937 monocytic cell line. View abstract. View abstract. Gastroenterol Rep (Oxf) 2019;7(4):298-300. doi: 10.1093/gastro/gox028. American Cancer Society; Shiitake Mushroom, "Journal of Allergy and Clinical Immunology"; Eosinophilia and Gastrointestinal Symptoms After Ingestion of Shiitake Mushrooms; A.M. Levy et al. View abstract. View abstract. View abstract. Murakami M, Kawabe K, Hosoi Y, et al. Although rare, shiitake mushroom intake has been associated with dermatitis and photosensitivity, according to an article published in the journal of "Dermatology." CONDITIONS OF USE AND IMPORTANT INFORMATION: Tooth plaque. JAAD Case Rep. 2015 May 2;1(3):117-9. View abstract. View abstract. 2015;34(6):478-87. 1996;16(4):224-226. Tochikura, T. S., Nakashima, H., Ohashi, Y., and Yamamoto, N. Inhibition (in vitro) of replication and of the cytopathic effect of human immunodeficiency virus by an extract of the culture medium of Lentinus edodes mycelia. Hamano, K., Gohra, H., Katoh, T., Fujimura, Y., Zempo, N., and Esato, K. The preoperative administration of lentinan ameliorated the impairment of natural killer activity after cardiopulmonary bypass. In vitro chemopreventive effects of plant polysaccharides (Aloe barbadensis miller, Lentinus edodes, Ganoderma lucidum and Coriolus versicolor). Carcinogenesis 1999;20:1637-40. Nihon Kokyuki.Gakkai Zasshi 2000;38(12):908-913. View abstract. The American Cancer Society notes that shiitake mushrooms are generally considered safe, although they may cause digestive distress, including bloating and diarrhea. Kanagawa Lentinan Research Group. 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